Multiparametric 3 Tesla magnetic resonance imaging as a clinical tool to characterize prostate cancer
نویسندگان
چکیده
......................................................................................................... v TABLE OF CONTENTS .......................................................................................vi LIST OF TABLES ............................................................................................... viii LIST OF FIGURES...............................................................................................ix LIST OF ABBREVIATIONS .................................................................................. x INTRODUCTION.................................................................................................. 1 The Prostate................................................................................................. 1 Cancer and the Prostate ............................................................................. 3 Socioeconomics .......................................................................................... 7 Molecules, Genetics, Race ......................................................................... 9 Categorizing the Malignancy.................................................................... 11 Imaging Technologies............................................................................... 17 MRI of the Prostate.................................................................................... 24 METHODS.......................................................................................................... 25
منابع مشابه
Prostate cancer detection at repeat biopsy: can pelvic phased-array multiparametric MRI replace saturation biopsy?
AIM Magnetic resonance imaging (MRI) accuracy in prostate cancer (PCa) diagnosis in men submitted to saturation prostate biopsy (SPBx) was evaluated. MATERIALS AND METHODS From June 2011 to December 2012, 78 patients (median 63 years) underwent repeat SPBx (median 28 cores). Multiparametric MRI using a 3 Tesla pelvic phased-array coil was performed before SPBx and lesions suspicious for PCa w...
متن کاملMultiparametric MR imaging for the assessment of prostate cancer aggressiveness at 3 Tesla
Introduction: Accurate assessment of aggressiveness of localized prostate cancer (PCa) is essential, because not all PCa is life-threatening and overtreatment of indolent disease should be prevented. The different functional magnetic resonance (MR) techniques, diffusion weighted imaging (DWI) [1,2], MR spectroscopic imaging (MRSI) [3] and dynamic contrast-enhanced (DCE)-MRI [4], show potential ...
متن کاملValue of PCA3 to Predict Biopsy Outcome and Its Potential Role in Selecting Patients for Multiparametric MRI
PCA3 (prostate cancer gene 3) and multiparametric 3 tesla MRI are new promising diagnostic tools in the detection of PCa. Our aim was to study the clinical value of the Progensa PCA3-test: its predictive value for biopsy outcome, Gleason score and MRI outcome. We evaluated, retrospectively, 591 patients who underwent a Progensa PCA3-test at the Radboud University Nijmegen Medical Centre between...
متن کاملMultiparametric magnetic resonance imaging: Current role in prostate cancer management.
Digital rectal examination, serum prostate-specific antigen screening and transrectal ultrasound-guided biopsy are conventionally used as screening, diagnostic and surveillance tools for prostate cancer. However, they have limited sensitivity and specificity. In recent years, the role of multiparametric magnetic resonance imaging has steadily grown, and is now part of the standard clinical mana...
متن کاملOptimization of clinical target volume delineation using magnetic resonance spectroscopic imaging (MRSI) in 3D conformal radiotherapy of prostate cancer
Background: For the purpose of individual clinical target volume assessment in radiotherapy of prostate cancer, MRSI was used as a molecular imaging modality with MRI and CT images. Materials and Methods: The images of 20 prostate cancer patients were used in this study. The MR and MRSI images were registered with CT ones using non-rigid registration technique. The CT based planning (BP), CT/MR...
متن کامل